Russell A DeBose-Boyd Selected Research

of Schnyder Crystalline Corneal Dystrophy

1/2020	Schnyder corneal dystrophy-associated UBIAD1 is defective in MK-4 synthesis and resists autophagy-mediated degradation.
1/2019	Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.
1/2018	UbiA prenyltransferase domain-containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids.
1/2016	Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi.
3/2015	The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Russell A DeBose-Boyd Research Topics

Disease

5	of Schnyder Crystalline Corneal Dystrophy 01/2020 - 03/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 06/2016
2	Neoplasms (Cancer) 01/2018 - 11/2013
2	Hypoxia (Hypoxemia) 01/2017 - 09/2007
1	Atherosclerosis 06/2016
1	Eye Diseases (Eye Disease) 01/2016
1	Carcinoma (Carcinomatosis) 11/2013
1	Prostatic Neoplasms (Prostate Cancer) 11/2013

Drug/Important Bio-Agent (IBA)

6	CholesterolIBA 01/2019 - 09/2007
3	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 01/2019 - 11/2013
3	Oxidoreductases (Dehydrogenase)IBA 01/2018 - 09/2007
3	SterolsIBA 06/2016 - 09/2007
2	Insulin (Novolin)FDA Link 01/2018 - 01/2017
2	Oxygen (Dioxygen)IBA 01/2017 - 09/2007
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 09/2007
1	Dietary CholesterolIBA 01/2021
1	geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA 01/2020
1	menatetrenoneIBA 01/2020
1	Dimethylallyltranstransferase (Dimethylallyltransferase)IBA 01/2020
1	Vitamin K 2 (Vitamin K2)IBA 01/2020
1	LipidsIBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2017
1	geranylgeraniolIBA 11/2013
1	DiterpenesIBA 11/2013
1	LanosterolIBA 09/2007
1	lanostenolIBA 09/2007
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 09/2007

Therapy/Procedure

2	Therapeutics 01/2021 - 11/2013
1	Chemoprevention 11/2013